Association of pre-existing depression and anxiety with Omicron variant infection (2024)

References

  1. Yang H, Chen W, Hu Y, Chen Y, Zeng Y, Sun Y, et al. Pre-pandemic psychiatric disorders and risk of COVID-19: a UK Biobank cohort analysis. Lancet Healthy Longev. 2020;1:e69–79.

    Article PubMed PubMed Central Google Scholar

  2. Chen W, Zeng Y, Suo C, Yang H, Chen Y, Hou C, et al. Genetic predispositions to psychiatric disorders and the risk of COVID-19. BMC Med. 2022;20:314.

    Article PubMed PubMed Central Google Scholar

  3. Lee SW, Yang JM, Moon SY, Yoo IK, Ha EK, Kim SY, et al. Association between mental illness and COVID-19 susceptibility and clinical outcomes in South Korea: a nationwide cohort study. Lancet Psychiatry. 2020;7:1025–31.

    Article PubMed PubMed Central Google Scholar

  4. Vai B, Mazza MG, Delli Colli C, Foiselle M, Allen B, Benedetti F, et al. Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis. Lancet Psychiatry. 2021;8:797–812.

    Article PubMed PubMed Central Google Scholar

  5. Jansen van Vuren E, Steyn SF, Brink CB, Möller M, Viljoen FP, Harvey BH. The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacological treatment. Biomed Pharmacother. 2021;135:111200.

    Article CAS PubMed PubMed Central Google Scholar

  6. Nudel R, Wang Y, Appadurai V, Schork AJ, Buil A, Agerbo E, et al. A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population. Transl Psychiatry. 2019;9:283.

    Article PubMed PubMed Central Google Scholar

  7. Arabi M, Al-Najjar Y, Mhaimeed N, Salameh MA, Paul P, AlAnni J, et al. Severity of the Omicron SARS-CoV-2 variant compared with the previous lineages: a systematic review. J Cell Mol Med. 2023;27:1443–64.

    Article CAS PubMed PubMed Central Google Scholar

  8. Goldberg EE, Lin Q, Romero-Severson EO, Ke R. Swift and extensive Omicron outbreak in China after sudden exit from ‘zero-COVID’ policy. Nat Commun. 2023;14:3888.

    Article CAS PubMed PubMed Central Google Scholar

  9. Pairo-Castineira E, Clohisey S, Klaric L, Bretherick AD, Rawlik K, Pasko D, et al. Genetic mechanisms of critical illness in COVID-19. Nature. 2021;591:92–8.

    Article PubMed Google Scholar

  10. COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19. Nature 2021;600:472–7.

  11. Feng Z, Ren X, Duren Z, Wang Y. Human genetic variants associated with COVID-19 severity are enriched in immune and epithelium regulatory networks. Phenomics. 2022;2:389–403.

    Article CAS PubMed PubMed Central Google Scholar

  12. Kousathanas A, Pairo-Castineira E, Rawlik K, Stuckey A, Odhams CA, Walker S, et al. Whole-genome sequencing reveals host factors underlying critical COVID-19. Nature. 2022;607:97–103.

    Article CAS PubMed PubMed Central Google Scholar

  13. Yang Y, Yuan M, Zeng Y, Xie Y, Xu Y, Liao D, et al. Cohort profile: the China Severe Trauma Cohort (CSTC). J Epidemiol. 2024;34:41–50.

    Article CAS PubMed PubMed Central Google Scholar

  14. Yang L, Chen W, Chen D, He J, Wang J, Qu Y, et al. Cohort profile: the China surgery and anesthesia cohort (CSAC). Eur J Epidemiol. 2024;39:207–18.

    Article PubMed PubMed Central Google Scholar

  15. Wang W, Bian Q, Zhao Y, Li X, Wang W, Du J, et al. Reliability and validity of the Chinese version of the Patient Health Questionnaire (PHQ-9) in the general population. Gen Hosp Psychiatry. 2014;36:539–44.

    Article PubMed Google Scholar

  16. Tong X, An D, McGonigal A, Park S-P, Zhou D. Validation of the Generalized Anxiety Disorder-7 (GAD-7) among Chinese people with epilepsy. Epilepsy Res. 2016;120:31–6.

    Article PubMed Google Scholar

  17. Wang S, Niu P, Su Q, He X, Tang J, Wang J, et al. Genomic Surveillance for SARS-CoV-2 - China, September 26, 2022 to January 29, 2023. China CDC Wkly. 2023;5:143–51.

    Article PubMed PubMed Central Google Scholar

  18. Sudlow C, Gallacher J, Allen N, Beral V, Burton P, Danesh J, et al. UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age. PLoS Med. 2015;12:e1001779.

    Article PubMed PubMed Central Google Scholar

  19. UK Biobnak. Mental health web-based questionnaire. 2017. https://biobank.ctsu.ox.ac.uk/crystal/refer.cgi?id=22. Accessed 5 Apr 2023.

  20. Moriarty AS, Gilbody S, McMillan D, Man ea L. Screening and case finding for major depressive disorder using the Patient Health Questionnaire (PHQ-9): a meta-analysis. Gen Hosp Psychiatry. 2015;37:567–76.

    Article PubMed Google Scholar

  21. Spitzer RL, Kroenke K, Williams JBW, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166:1092–7.

    Article PubMed Google Scholar

  22. Nahum M, Van Vleet TM, Sohal VS, Mirzabekov JJ, Rao VR, Wallace DL, et al. Immediate mood scaler: tracking symptoms of depression and anxiety using a novel mobile mood scale. JMIR mHealth uHealth. 2017;5:e6544.

    Article Google Scholar

  23. The COVID-19 Host Genetics Initiative, Andrea Ganna. A second update on mapping the human genetic architecture of COVID-19. medRxiv. 2022:2022.12.24.22283874.

  24. Mak TSH, Porsch RM, Choi SW, Zhou X, Sham PC. Polygenic scores via penalized regression on summary statistics. Genet Epidemiol. 2017;41:469–80.

    Article PubMed Google Scholar

  25. WHO. Historical working definitions and primary actions for SARS-CoV-2 variants. 2023. https://www.who.int/publications/m/item/historical-working-definitions-and-primary-actions-for-sars-cov-2-variants. Accessed 5 Apr 2023.

  26. Allaoui M, Kherfi ML, Cheriet A. Considerably improving clustering algorithms using UMAP dimensionality reduction technique: a comparative study. In: El Moataz A, Mammass D, Mansouri A, Nouboud F, editors. Image and signal processing; 2020; Cham: Springer International Publishing; 2020. p. 317–25.

  27. Whitaker M, Elliott J, Bodinier B, Barclay W, Ward H, Cooke G, et al. Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England. Nat Commun. 2022;13:6856.

    Article CAS PubMed PubMed Central Google Scholar

  28. Giannakopoulou O, Lin K, Meng X, Su MH, Kuo PH, Peterson RE, et al. The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study. JAMA Psychiatry. 2021;78:1258–69.

    Article PubMed Google Scholar

  29. Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, et al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nat Genet. 2018;50:668–81.

    Article CAS PubMed PubMed Central Google Scholar

  30. e Silva NML, Barros-Aragão FG, De Felice FG, Ferreira ST. Inflammation at the crossroads of COVID-19, cognitive deficits and depression. Neuropharmacology. 2022;209:109023.

    Article Google Scholar

  31. Proust A, Queval CJ, Harvey R, Adams L, Bennett M, Wilkinson RJ. Differential effects of SARS-CoV-2 variants on central nervous system cells and blood–brain barrier functions. J Neuroinflammation. 2023;20:184.

    Article CAS PubMed PubMed Central Google Scholar

  32. Flacco ME, Acuti Martellucci C, Baccolini V, De Vito C, Renzi E, Villari P, et al. Risk of reinfection and disease after SARS‐CoV‐2 primary infection: Meta‐analysis. Eur J Clin Investig. 2022;52:e13845.

    Article CAS Google Scholar

  33. Liu L, Ni SY, Yan W, Lu QD, Zhao YM, Xu YY, et al. Mental and neurological disorders and risk of COVID-19 susceptibility, illness severity and mortality: A systematic review, meta-analysis and call for action. EClinicalMedicine. 2021;40:101111.

    Article PubMed PubMed Central Google Scholar

  34. Keller J, Gomez R, Williams G, Lembke A, Lazzeroni L, Murphy GM, et al. HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition. Mol Psychiatry. 2017;22:527–36.

    Article CAS PubMed Google Scholar

  35. He Y, Zhang F, Liu Y, Xiong Z, Zheng S, Liu W, et al. Clinical characteristics of mild patients with breakthrough infection of omicron variant in china after relaxing the dynamic zero COVID-19 policy. Vaccines. 2023;11:968.

    Article PubMed PubMed Central Google Scholar

  36. Ceban F, Nogo D, Carvalho IP, Lee Y, Nasri F, Xiong J, et al. Association between mood disorders and risk of COVID-19 infection, hospitalization, and death: a systematic review and meta-analysis. JAMA Psychiatry. 2021;78:1079–91.

    Article PubMed PubMed Central Google Scholar

  37. Thi Hong Nguyen N, Ou T-Y, Huy LD, Shih C-L, Chang Y-M, Phan T-P, et al. A global analysis of COVID-19 infection fatality rate and its associated factors during the Delta and Omicron variant periods: an ecological study. Front Public Health. 2023;11:1145138.

    Article Google Scholar

  38. Menni C, Valdes AM, Polidori L, Antonelli M, Penamakuri S, Nogal A, et al. Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study. Lancet. 2022;399:1618–24.

    Article CAS PubMed PubMed Central Google Scholar

  39. Miller AH. Beyond depression: the expanding role of inflammation in psychiatric disorders. World Psychiatry. 2020;19:108–9.

    Article PubMed PubMed Central Google Scholar

  40. Hong H, Kim BS, Im HI. Pathophysiological role of neuroinflammation in neurodegenerative diseases and psychiatric disorders. Int Neurourol J. 2016;20:S2–7.

    Article PubMed PubMed Central Google Scholar

  41. Zhang AJ, Lee AC-Y, Chu H, Chan JF-W, Fan Z, Li C, et al. Severe acute respiratory syndrome coronavirus 2 infects and damages the mature and immature olfactory sensory neurons of hamsters. Clin Infect Dis. 2021;73:e503–12.

    Article CAS PubMed Google Scholar

  42. Song WJ, Hui CKM, Hull JH, Birring SS, McGarvey L, Mazzone SB, et al. Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses. Lancet Respir Med. 2021;9:533–44.

    Article CAS PubMed PubMed Central Google Scholar

  43. Driessen AK, Devlin A-C, Lundy FT, Martin SL, Sergeant GP, Mazzone SB, et al. Perspectives on neuroinflammation contributing to chronic cough. Eur Respir J. 2020;56:2000758.

  44. Song H, Fall K, Fang F, Erlendsdóttir H, Lu D, Mataix-Cols D, et al. Stress related disorders and subsequent risk of life threatening infections: population based sibling controlled cohort study. BMJ. 2019;367:l5784.

  45. Deng Y, Chen Y, Zhang B. Different prevalence trend of depression and anxiety among healthcare workers and general public before and after the peak of COVID-19 occurred in China: a meta-analysis. Asian J Psychiatry. 2021;56:102547.

    Article Google Scholar

  46. Fu D, He G, Li H, Tan H, Ji X, Lin Z, et al. Effectiveness of COVID-19 vaccination against SARS-CoV-2 Omicron variant infection and symptoms - China, December 2022-February 2023. Chin a CDC Wkly. 2023;5:369–73.

    Article Google Scholar

  47. Sichuan Center for Disease Control and Prevention. Results of Sichuan Province COVID-19 Infection Status Questionnaire Survey. 2022. https://www.sccdc.cn/Article/View?id=26473. Accessed 5 Feb 2024.

  48. Batty GD, Gale CR, Kivimäki M, Deary IJ, Bell S. Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis. BMJ. 2020;368:m131.

Download references

Association of pre-existing depression and anxiety with Omicron variant infection (2024)
Top Articles
Latest Posts
Article information

Author: Kieth Sipes

Last Updated:

Views: 5965

Rating: 4.7 / 5 (47 voted)

Reviews: 94% of readers found this page helpful

Author information

Name: Kieth Sipes

Birthday: 2001-04-14

Address: Suite 492 62479 Champlin Loop, South Catrice, MS 57271

Phone: +9663362133320

Job: District Sales Analyst

Hobby: Digital arts, Dance, Ghost hunting, Worldbuilding, Kayaking, Table tennis, 3D printing

Introduction: My name is Kieth Sipes, I am a zany, rich, courageous, powerful, faithful, jolly, excited person who loves writing and wants to share my knowledge and understanding with you.